Issues with the VDR and the intracellular machinery and to overcome these defects is discussed here: : https://judsonsomerville.com/vitamin-d3-vitamin-d-receptors-and-why-you-may-not-see-results-from-taking-optimal-doses-of-vitamin-d3-1-2/ That by overcoming these defects allows activation of vitamin D3 and initiation of its gene expression. The blog posting is two parts...
Read moreAs I was discussing at the end of the last blog post defects in the vitamin D receptor (VDR), machinery that modifies the active form of vitamin D3 so it can activate the VDR and vitamin D3 deficiency can result...
Read moreAt the time I did that I had not put my understanding of cancer all together yet. Well, cancer cells or at least many I have found so far significantly increase for one the production of the 24-hydroxylase enzyme produced...
Read moreTo digress, as I mentioned in the first blog post of this series the reason, I have not blogged about vitamin D3 and its direct role in destroying/preventing cancer, is because it was not clear to me how vitamin D3 Read more…
Taking skin cells as an example in skin cells-keratinocytes-all three main forms of vitamin D3 activate the HPA axis and the peripheral cellular process where this occurs to produce pro-opiomelanocortin (POMC). 1 To summarize the three main forms of vitamin Read more…