How Beta-endorphins are formed is where things get interesting. They are produced from the cleaving of a substance pre-pro-opiomelanocortin produced in the pituitary into pro-opiomelanocortin (POMC) a peptide neurotransmitter. Ok no big deal. But what I learned next was the stunner. See the tumor suppressor gene called p53 gene is Read more…
Not a typical combination of things. Two classes of diseases, a vitamin (hormone) and a natural phenomenon. I have grouped them together to try to better understand their connection, as there is one. There are many connections which makes explaining them difficult, but I will try. So hang on. I Read more…
Activities like exercise and sleep. I would argue for all if medically able to, but especially those who cannot or do not do moderate exercise, optimal blood levels of vitamin D3. Vitamin D3 is not the only factor important to obtain adequate DRS allowing the glymphatic drainage system (GDS) to Read more…
Thus, with inadequate deep restorative sleep (DRS) some people were more susceptible to this protein build up than others. That gave me the idea that these diseases, proteinopathies, are perhaps different expressions of an combination of inadequate DRS, loss of or malfunctioning glymphatic drainage system (GDS) and how that affected Read more…
As I wrote in an earlier post on deep restorative sleep (DRS), https://judsonsomerville.com/sleep/. To give a brief refresher, remember as a kid being awoken from a DEEP sleep? How you took a few moments to orient? I believe that is because your brain was partially or completely contracted and once Read more…