So, my thinking was to restore balance I would take again higher vitamin D3 doses. Thus, I would resolve the issue if some of the vitamin D3 was being diverted. My friend that stopped the additional vitamin K2 both MK-4 and MK-7 types. Soon after stopping both types of vitamin K2 my friend was back to normal.
Back to where they had the usual great benefits from vitamin D3 at optimal doses. Me no help. Thus, after a week of this increased vitamin D3 I too stopped both the MK-4 and MK-7 types of vitamin K2. If you’re use to horrible sleep that is one thing but after years of great sleep it hits harder to regress.
Almost immediately my sleep returned and gradually my pain is resolving. Initially it was a significant drop in pain but now more gradual. Whereas at one point intolerable now tolerable but still not to my pre vitamin K the MK-4 experiment levels.
Based on these rapid responses in both of us has led me to believe initially, the addition of vitamin K2 both the MK-4 and MK-7 types was the cause of loss of sleep, weight gain and bone pain. I looked on the internet but could find no explanation. Perhaps adding the MK-4 type in some cases issues.
As I have since added back only the vitamin K2 MK-7 type as the peripheral vascular disease appears to be resolving. What little I had left. I believe that the vitamin K2 the MK-7 type may help some but perhaps not those who have no symptoms when taking optimal doses with optimal blood levels of vitamin D3.
I have seen a few people who started vitamin D3 at optimal doses initially develop bone pain but only a hand full out of thousands. At the time I really had no explanation for why it happened or how to prevent it. Maybe I do now. So, I recently contacted a few of those who had that initial bone pain.
I recommended they add vitamin K2 the MK-4 type to see if it helps. That was before my recent experiences. So, I need to check what was their reaction. My issue is though I believe that bone “remineralization” could initially cause pain in some, I don’t believe it should continue to months later.
Yes, some argue adding higher doses of vitamin D3 causes inflammation of the periosteum. Yes, there are sensitive nerve endings there. But if it were common and, in the population, I have recommended optimal doses of vitamin D3 it should have been common.
My experience shows adding vitamin K2 the MK-4 type at least after having taken optimal doses of vitamin D3 for years can cause issues like bone pain and reversing the positive effects of optimal dosing and blood levels of vitamin D3.
As most of those I treated in the past were older, probably average age in 60’s, and had varying degrees of osteoporosis. In fact, bone pain was not common, but extremely rare. My years of clinical experience treating patients does have value.
As in as many people as I had treated if a problem like this is common then I would have had seen many experiences it. I did not.
Yes, even though a large group it was still not all people. It could be the people I treated have some special genetic trait that makes them immune to bone pain.
But I doubt it. Since I did not see but a few with bone pain upon starting optimal dosing of vitamin D3.
Of note I always had those taking optimal dosing of vitamin D3 at the same time to maximize their dose of magnesium when able. Work up to taking usually 1.6-3 grams a day.
*The information posted above is for educational purposes only. Always check with your doctor before initiating any changes in your medical treatment. If you do not, then The Two-Minute Health Fact, Dr. Judson Somerville, nor The Optimal Dose is responsible!
2 Comments
P. Raghavan. · January 16, 2020 at 8:24 am
There is an article available in the net “Study shows Probiotic L. Reuteri significantly increase vitamin D level “. This article says that L. Reuteri increase vitamin D3 level by 25.5 % over the nine-week intervention in a human trial. There is another article available in the net “Production of Menaquinones (vitamin K2) by lactic acid bacteria”. This article states Vitamin K2 is synthesized by Probiotic Lactococcus Lactis. One can take probiotic tablets containing both strains. There are brands like Innate Vitality Women’s probiotic, Terranics Probiotics, etc. available online. This is a good alternative.
Jason · November 7, 2022 at 7:36 pm
That is so bizarre about the Mk4 K2 causing you to backslide like that. So it sounds like you tolerated the Mk7 ok though? And am I hearing you correctly at the end of this blog, you say to work up to 1.6-3 grams of magnesium a day? That’s quite a bit higher than I’ve ever seen recommended, even by a nutritionist (Andrew Saul). What makes you target that high of a dose, just out of curiosity? I’m currently working on my magnesium supplementation, and have really looked into this a lot, but there are really no studies on higher level dosing I can find. I know Andrew Saul takes about 1.5 grams a day, usually.